About Pharmacology Study of drugs and their orgin, including its nature, properties and effects on living organisms, it studies and evaluates the drugs potential therapeutic value and throws light in the discovery, composition, identification, biological / physioogical effects and use of drugs. Objectives The broad goal of the teaching of undergraduate students in Pharmacology is to inculcate a rational and scientific basis of therapeutics. Course Contents
At the end of the course, the student shall be able to :
Describe the pharmacokinetics and pharmacodynamics of essential and commonly used drugs :
List of indications, contraindications, interactions and adverse reactions of commonly used drugs :
Indicate the use of appropriate drug in a particular disease with consideration to its cost effieasy and safety for
Mass therapy under national health programme
Describe the pharmacokinetic basis, clinical presentations, diagnosis and management of common poisonings.
List the drugs of addiction and recommend the management.
Classify environmental and occupational pollutants and state the management issues.
Indicate causation in prescription of drugs in special medical situations such as pregnancy, lactation, infancy and old age.
Integrate the concept of rational drug therapy in clinical pharmacology State the principles underlying the concept of "Essential Drugs".
Evaluate the ethics and modalities in the development and introduction of new drugs.
1. GENERAL PRINCIPLES
c) Principles of therapeutics
d) Concepts of essential drugs and rational drug therapy
e) Special aspects of drugs in pregnancy, pertinatal pediatric and geriatric pharmacology.
f) Ethics and modalities of new drug development
g) Adverse reactions to drugs and common drug interactions.
2. DRUGS ACTING AT SYNAPTIC AND NEURO EFFECTOR JUNCTION
a) Cholinergic and anticholinergic drugs
b) Adrenergics and adrenergic blockers
c) Drugs acting at Neuromuscular Junction and autonomic ganglia.
3. OCULAR PHARMACOLOGY
4. DRUGS ACTING ON CENTRAL NERVOUS SYSTEM
a) General anesthetics
b) Local anesthetics
c) Hypno sedatives
d) Drugs and treatment of psychiatric disorders - psychosis, depression and mania.
e) Drugs in the therapy of epilepsies
f) Drugs in the therapy of migraine
g) Drugs in the central nervous system degenerative disorders
h) Opioid analgesics and antagonists
i) Drug addiction and treatment
a) Histamine, Bradykinin, 5 HT and their antagonists
b) Lipid derived autocoids
c) Analgesic - antipyretic and anti inflammatory agents
6. DIURETICS AND OTHER AGENTS AFFECTING RENAL CONSERVATION OF WATER
7. DRUGS ACTING ON CARDIOVASCULAR SYSTEM INCLUDING BLOOD
a) Drugs used for treatment of Myocardial ischemia, heart failure
b) Anti arrhythmic drugs
c) Anti hypertensives
d) Lipid lowering drugs
e) Drug Therapy of shock
f) Hematopoietic agents (growth factors, minerals and vitamins)
g) Anticoagulants, Thrombolytic and antiplatelet drugs
8. DRUG ACTING ON RESPIRATORY SYSTEM
a) Pharmacotherapy of cough
b) Pharmacotherapy of bronchial asthma
9. THERAPEUTIC GASES
10 . DRUGS AFFECTING GASTROINTESTINAL FUNCTION
a) Chemotherapy of microbial diseases
b) Chemotherapy of parasitic infections
c) Chemotherapy of neoplastic diseases
d) Antiseptics and disinfectants
12. DERMATOLOGICAL PHARMACOLOGY
13. DRUGS USED FOR IMMUNOMODULATION
14. ENDOCRINE PHARMACOLGY
a) Hypothalamic and pituitary hormones.
b) Thyroid and antityroid drugs
c) Adreno corticosteroids and their antagaonists
d) Gonadal hormones and inhibitors
e) Panerealic hormones, and antidiabetic drugs
f) Agents that effect bone mineral homeostasis
15. ENZYMES IN THERAPY
a) Principles of toxicology and treatment of poisoning
b) Heavy metals and antagonists.
c) Non metallic environmental toxicants.
1) Drugs used in Parkinsonism
2) Drugs used in gout and (Rheumatoid arthritis)
SYLLABUS IN PRACTICAL PHARMACOLOGY
1) Prescription writing for common ailments.
2) Prescription audit
3) Patient oriented problems relating to adverse drug reactions and common drug interactions.
4) Experiments designed for study of effects of drugs.
5) Critical evaluation of drug formulations
6) Dosage calculations
7) Pharmaco economic problems
8) Interpretation of clinical pharmacology data
At the end of the course, the student shall be able to.
Prescribe drug for common ailments.
Recognize adverse reactions and interactions of commonly used drugs.
Observe experiments designed for study of effects of drugs, bio-assay and interpretation of the experimental data.
Scan information on common pharmaceutical preparations and critically evaluate drug formulations.
Teaching & Learning methods
The following objectives will be covered using theory lectures, small group discussions, simulated clinical case discussions, therapeutic auditing, problem based learning, e-learning and any other teaching learning method which the teacher chooses to select. An overlap between theory and practical classes will serve to reinforce and complement the two. Points not covered in theory can be covered during practical classes.
Integration: During the 7th and 8th semesters, clinical pharmacology with major focus on therapeutics will be taught. This will be done by integrated teaching wherein departments of Pharmacology, Medicine, Psychiatry, Paediatrics etc will come together and discuss common clinical problems in the form of case discussion. The focus will be on therapeutics.
Pharmacology | Pathology | Microbiology | Forensic Medicine | Community Medicine
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